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LibraryFamily 1 · Diagnostic Imaging & Pathology

Digital pathology decision support for prostate cancer

CuratedPilotEmerging evidence

Reviewed for completeness and published to the Library.

Highlights tissue regions on digitised prostate biopsy slides suspicious for cancer to support the reporting pathologist.

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Clinical context
Clinical problem
Detect a condition
Point of care
Diagnosis
Nature of AI output
A classification
Clinical specialty
Pathology
Care setting
Hospital — outpatient
Patient population
Prostate core needle biopsy specimens from men referred for suspected prostate cancer.
Intended use
Highlights tissue regions on digitised prostate biopsy slides suspicious for cancer to support the reporting pathologist.
Technology
AI technique
Deep learning, Computer vision
Input data
Medical imaging
Output type
Classification
Autonomy level
Informs a human (advisory)
Model provenance
Vendor proprietary
Model version
Prostate v2.0
Built on a general-purpose model
No
Deployment
Status
Pilot
Country
Sweden
Deployment date
10 February 2025
Sites
1
Regulatory & governance
EU AI Act risk tier
High-risk
High-risk basis
Annex I — medical device
Medical device
Yes
EU MDR class
Class IIa
CE marking
CE marked
FDA status
De Novo
ISO 14971 risk class
Not assessed
GDPR processing basis
Public interest
GDPR DPIA
Completed
Data identifiability
Pseudonymised
Explainability method
Post-hoc
Human oversight model
Pathologist reviews every slide; AI output is an overlay, not a diagnosis.
NICE evidence standards
ESF tier
Tier C — treat / diagnose / calculate risk
Evidence category
Performance summary
Headline metric
AUC / AUROC
Value
0.97
Subgroup performance assessed
No
Known bias signals

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Evidence records

Studies and evaluations attached to this use case.

  • Retrospective validation

    AUC / AUROC: 0.97

    Population: Prostate biopsy slides, 2k specimens

Contributors

Deploying organisation
[demo] Karolinska University Hospital · Hospital / health system · Sweden
AI vendor
[demo] Paige AI · United States
Product name
Paige Prostate