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LibraryFamily 5 · Medication Safety & Optimisation

Prescribing decision support — drug interaction alerts

CuratedPilotNo evidence on file

Reviewed for completeness and published to the Library.

Screens new prescriptions against the medication list and patient parameters to alert prescribers to clinically significant drug interactions.

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Clinical context
Clinical problem
Detect a condition
Point of care
Treatment planning
Nature of AI output
An alert
Clinical specialty
Pharmacy
Care setting
Hospital — inpatient
Patient population
Adult inpatients with active prescriptions, with emphasis on polypharmacy and renally-impaired patients.
Intended use
Screens new prescriptions against the medication list and patient parameters to alert prescribers to clinically significant drug interactions.
Technology
AI technique
Rule-based, Classical machine learning
Input data
Structured EHR data, Laboratory results
Output type
Alert
Autonomy level
Informs a human (advisory)
Model provenance
Built in-house
Model version
Built on a general-purpose model
No
Deployment
Status
Pilot
Country
Denmark
Deployment date
1 April 2025
Sites
1
Regulatory & governance
EU AI Act risk tier
Not assessed
High-risk basis
Not applicable
Medical device
No
EU MDR class
Not a device
CE marking
Not required
FDA status
Not applicable
ISO 14971 risk class
Not assessed
GDPR processing basis
Legal obligation
GDPR DPIA
Not required
Data identifiability
Pseudonymised
Explainability method
Intrinsic
Human oversight model
Interruptive alert at the point of prescribing; the prescriber accepts or overrides with a reason.
NICE evidence standards
ESF tier
Tier B — inform / monitor
Evidence category
Performance summary
Headline metric
Positive predictive value
Value
0.68
Subgroup performance assessed
No
Known bias signals
High override rate observed for low-severity alerts; tiering of alert severity under review to reduce fatigue.

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Contributors

Deploying organisation
[demo] Aarhus University Hospital · Hospital / health system · Denmark
AI vendor
Product name